Commercial Laboratory Environmental Controls in Glendale, CA

Laboratory environments leave no room for guesswork. #1 AC Guys engineers, builds, and services environmental control systems that hold tight setpoints, protect pressure cascades, and deliver the air changes and filtration your protocols demand—all while improving energy performance and lifecycle reliability. From concept to commissioning and through ongoing service, we are your single accountable partner in Glendale.

Design–Build for Precision and Compliance

Our process starts with a detailed needs assessment: occupancy and process loads, target temperature/humidity bands, ISO class or USP 797/800 requirements, air change targets, exhaust sources, and pressure zoning. We translate this into a resilient design with redundancy where it matters most, materials compatible with clean applications, and controls logic that protects both people and product.

• Cleanrooms (ISO 14644) and controlled environments
• USP 797/800 compounding pharmacies and negative/positive pressure rooms
• BSL research spaces, vivariums, and microelectronics labs
• Instrument rooms, stability chambers, and sample prep areas
• Corrosive, solvent, and hazardous exhaust strategies with make‑up air

We deploy VRF/heat‑recovery, DOAS, terminal HEPA fan filter units, low‑leak VAV valves, reheat, steam or electrode humidification, and desiccant dehumidification where needed. Our engineers trained at the factories of Fujitsu (Japan), Mitsubishi Elektrik (Thailand), Midea (China), Gree (China), and Hier (China), ensuring the equipment we specify is applied the right way from day one.

Controls, Monitoring, and Data You Can Trust

We integrate open‑protocol controls (BACnet/Modbus) with your Building Management System to surface real‑time trends, alarms, and reports. Spaces are protected with pressure monitors, humidity/temperature sensors, and fail‑safe sequences that maintain directional airflow and containment during disturbances.

• 24/7 monitoring and alerting for pressure, humidity, and temperature
• Room‑level dashboards and audit‑friendly data logs
• N+1 strategies for fans, filtration, and critical components
• Energy optimization without compromising compliance

We provide commissioning plans, functional performance testing, and owner training. We also support your third‑party certification and validation partners with submittals, air balance reports, and controls documentation to streamline ISO 14644 and USP 797/800 compliance workflows.

Installation, Retrofits, and Phased Upgrades

Working in active labs requires careful phasing and containment. Our team sequences work to minimize downtime and protect clean operations while replacing equipment, adding HEPA terminals, or reworking duct and exhaust paths. We coordinate closely with your safety and QA teams to maintain pressure differentials and cleanliness during construction.

• Packaged rooftop and split systems integrated with DOAS
• VRF and heat‑recovery for precise zone control
• Terminal HEPA/ULPA modules and low‑leak ductwork
• Make‑up air, fume hood/exhaust balancing, and heat recovery wheels
• Seismic bracing and code‑compliant supports for California

Our Glendale‑focused crews are accustomed to the permitting process across Los Angeles County and nearby jurisdictions. Expect clear timelines, jobsite cleanliness, and engineering oversight at every step.

Maintenance that Protects Uptime

Precision environments demand proactive service. We tailor maintenance plans to your SOPs and risk profile, with scheduled filter changes, calibration checks, pressure tuning, and seasonal start‑ups. Our goal: stable conditions, fewer surprises, and data to prove performance.

• GMP‑minded service documentation and change control support
• Critical spares planning and rapid response for Glendale facilities
• Sensor calibration and air balance tune‑ups
• Lifecycle planning to forecast capital needs

As a fourth‑generation family business with 80+ years in engineering, we stand behind our work with transparent communication and measurable results. Healthy, precise air is our mission—because reliable science, production, and patient safety depend on it.

Who We Serve

We support biotechnology and pharma R&D, compounding pharmacies, hospitals, diagnostic and analytical labs, microelectronics and optics, food and beverage testing, and university research facilities. While Glendale is home base, we serve Los Angeles County and nearby regions, including Orange County, Ventura County, and Western Riverside County.

Why #1 AC Guys

• 80+ years of engineering and a fourth‑generation family team
• Factory training with Fujitsu (Japan), Mitsubishi Elektrik (Thailand), Midea (China), Gree (China), and Hier (China)
• Design‑build delivery with commissioning and documentation support
• Controls expertise, BMS integration, and audit‑ready data
• Specialists in complex, large‑scale, and high‑stakes projects

Let’s engineer your next laboratory environment in Glendale with confidence. Tell us your target specs and constraints, and our team will provide a clear scope, timeline, and budget—designed for precision, safety, and long‑term value.
Contact #1 AC Guys to schedule an on‑site assessment or request a detailed proposal.