Pasadena Commercial Laboratory Environmental Controls

#1 AC Guys delivers precise, reliable environmental control for Pasadena laboratories—cleanrooms, vivariums, healthcare compounding suites, academic research cores, and high-containment spaces. Our solutions balance temperature, humidity, airflow, and pressurization to protect product integrity, staff safety, and research repeatability while optimizing energy consumption and uptime.

What we engineer for your lab

We specialize in tightly controlled air systems designed for scientific work. That means stable setpoints, fast recovery after door openings, and quiet, predictable performance that integrates into the way your team operates every day.
Our approach is practical, data-driven, and engineered for Pasadena’s code environment and Southern California’s climate.

• Cleanroom HVAC with ISO 14644-focused design (temperature, humidity, ACH, and particle control)
• Positive and negative pressure rooms with precise differential pressure monitoring
• HEPA/ULPA filtration, laminar flow, and make-up air systems
• VAV fume hood control and exhaust air energy recovery
• Humidification/dehumidification to tight tolerances for sensitive processes
• BACnet/BMS integration, alarming, and trend logging
• Redundancy strategies (N+1) for critical environments and equipment
• Commissioning, balancing, and validation-ready documentation

Fourth-generation engineers. 80+ years of engineering expertise.

As a fourth-generation family of engineers, we bring 80+ years of engineering knowledge to every commercial project. Our senior specialists have been factory-trained at: Fujitsu (Japan), Mitsubishi Elektrik (Thailand), Midea (China), Gree (China), and Hier (China). This background drives our attention to detail, from psychrometrics and heat load modeling to control sequences that hold your targets steady without wasting energy.

AC PRO integration for Pasadena facilities

We design, install, and service solutions that incorporate AC PRO equipment and components widely used across Southern California. Whether it’s air handlers, condensers, filtration assemblies, or controls integration, our team aligns AC PRO–sourced hardware with your laboratory’s performance and compliance objectives, all while ensuring maintainability and spare-parts availability through local supply channels.

Design–Build–Service: one accountable team

From concept to turnover, you work with one accountable engineering-led team. We begin with a discovery session and on-site assessment, then deliver load calculations, airflow diagrams, and control sequences tailored to your protocols. Our installation crews coordinate around your schedule, minimizing downtime for active research. After start-up, we commission, balance, and trend critical points to verify real-world performance.

• New construction and tenant improvements
• Retrofits and rebalancing for existing labs
• Cleanroom upgrades to support changing classifications
• Fume hood diversity strategies to reduce energy use
• Heat recovery and demand-controlled ventilation

Controls, data, and integration

Reliable controls make or break a laboratory environment. We implement sequences for stable temperature and humidity, cascade pressurization, setback modes, and safe shutdown/startup procedures. Our systems integrate with your BACnet BMS for centralized monitoring, alarms, and trending. We also provide role-based access and clear naming standards so your facility team can operate with confidence.

Compliance support without the guesswork

While compliance is ultimately verified by your third-party specialists, our designs are aligned with prevailing standards and guidelines such as ISO 14644 for cleanrooms, USP <797>/<800> for compounding, ASHRAE fundamentals and laboratory best practices, and California Title 24 energy requirements. We document airflow, pressure relationships, filtration, and control logic to support validation and audits.

Preventive maintenance and 24/7 response

Protect your research and production with proactive service. Our maintenance plans include scheduled filter changes, coil cleaning, calibration of sensors and transmitters, verification of differential pressure and airflow, and control sequence testing. When minutes matter, our Pasadena dispatch delivers 24/7 emergency response with parts access through AC PRO supply channels for faster turnarounds.

Built for Southern California labs

Headquartered in Los Angeles, we serve Pasadena and the broader region—Los Angeles County and nearby areas including Orange County, Ventura County, and Western Riverside County. Local code knowledge, local crews, local parts availability: it all adds up to faster projects and steadier uptime.

Our mission: healthy air for a healthy life

In laboratories, healthy air means predictable environments and cleaner outcomes. That’s why every #1 AC Guys solution aims to safeguard people and science with superior air quality, stable conditions, and energy-smart control. Tell us your target specs—temperature, RH, air changes, pressure—and we’ll engineer a path to get you there.

Get started today

Request an engineer-led assessment of your Pasadena facility. We’ll review current performance, identify risks and efficiency opportunities, and provide a clear proposal with phasing options to minimize disruption. Complex requirements are where we excel—bring us your toughest laboratory HVAC challenge.